DMCA. Copyrighted Work that you can Claim.
Base have 250 515 books.
Search: 


📙 Cytokines and Growth Factors in Blood Transfusion: Proceedings of the Twentyfirst International Symposium on Blood Transfusion, Groningen 1996, organized by the Red Cross Blood Bank Noord Nederland by B. Blom, H. Spits, P. Krimpenfort (auth.), Dr. Cees Th. Smit Sibinga, P. C. Das, Prof.Dr. Bob Löwenberg (eds.) — epub download


Cytokines are cellular growth factors which also provide communication between cells and their milieu. This clearly is an exciting area in modern medicine that will have significant impact on various facets of transfusion. Erythropoietin therapy stimulates red cell production while thrombopoietin seems to positively affect megakaryopoiesis and can be an added armamentarium for the thrombocytopenic patient.
Using haematnopoietic growth factors, stem cells could be mobilized early to the peripheral blood for collection and subsequent transplantation into haemato-oncology patients instead of bone marrow transplantation. Using a cocktail of cytokines in cell culture, stem cells could be expanded and selected for therapy. Cytokines and growth factors can even be modified, which may lead to successful gene therapy in malignancies, including solid tumour vaccines. However, the presence of cytokines in certain blood products could have biological effects following transfusion, although its clinical relevance needs to be ascertained. There is much potential for the use of cytokines in the treatment of infections. Early diagnostic methods are now available to monitor their levels and relevance. It is likely that cytokines will increasingly play a role in therapy and could develop our fundamental knowledge about the development of T-cells. An ethical dilemma remains, however, regarding the use of cytokines in healthy donors for harvesting suitable specific cells. Longer clinical observation will be necessary to gather the necessary information.
Cytokines and growth factors in blood transfusion was the theme of the 21st International Symposium in Blood Transfusion, where twenty clinicians and scientists, experts in their own fields, were invited to update the above information. Their findings are presented in four sections in this volume:

  • Fundamental aspects - cytokines in development of T-cells, growth factors in haematopoiesis, growth factor receptors and signal transduction, cytokine response in platelet and whole blood transfusions.
  • Function, production and diagnosis &endash; laboratory diagnostics of cytokines and growth factors, cytokines in blood components, cytokines and growth factors in cell expansions, cytokines for genetic modification towards gene therapy, progenitor cells from healthy donors.
  • Application in clinical medicine &endash; clinical relevance of cytokines in transfusion products, cytokines and growth factors in solid tumours, gene therapy in malignancies, vaccine strategies inducing T-cell immunity against tumours, cytokines in the treatment of infections, thrombopoietin and megakaryopoiesis.
  • Future potential use in transfusion medicine &endash; erythropoietin, immunotherapy, ethical aspects of the use of cytokines and growth factors in donors, potential of cytokines and growth factors in transfusion medicine.



About file:

  • File size: 5 342 076
  • Format: pdf


Security code:
Download button

Similar books results


Paediatrics and Blood Transfusion: Proceedings of the Fifth Annual Symposium on Blood Transfusion, Groningen 1980 organized by the Red Cross Bloodbank Groningen-Drenthe
Paediatrics and Blood Transfusion: Proceedings of the Fifth Annual Symposium on Blood Transfusion, Groningen 1980 organized by the Red Cross Bloodbank Groningen-Drenthe download pdf by B. Broman (auth.), C. Th. Smit Sibinga, P. C. Das, John O. Forfar (eds.)

The practice of transfusing blood started at the bedside but over the last few decades blood transfusion has become more and more a laboratory directed discipline. The emphasis on serology and laboratory controlled measures has made blood transfusion safe...

Systems, Part AB (Growth Factors & Cytokines in Health & Disease) (Growth Factors & Cytokines in Health & Disease)
Systems, Part AB (Growth Factors & Cytokines in Health & Disease) (Growth Factors & Cytokines in Health & Disease) free download by D. LeRoith, C. Bondy

This volume deals with some of the multiple systems that growth factors and cytokines affect. The role of growth factors and cytokines on foetal development, in the immune and haemopoietic systems as well as in the skeletal and reproductive systems are co...

Neonatology and Blood Transfusion (Developments in Hematology and Immunology, Vol. 39)
Neonatology and Blood Transfusion (Developments in Hematology and Immunology, Vol. 39) download pdf by C. Th. Smit-Sibinga

Proceedings of the Twenty-Eighth International Symposium on Blood Transfusion, Groningen, NL, Organized by the Sanquin Division Blood Bank North-East, Groningen. It is in many ways fitting that the last of these international symposia on blood transfusio...

Peptide Growth Factors and Their Receptors II
Peptide Growth Factors and Their Receptors II free pdf by J. VilÄŤek (auth.), Michael B. Sporn M. D., Anita B. Roberts Ph. D. (eds.)

This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, a...

Alternatives to Blood Transfusion in Transfusion Medicine, Second Edition, Second Edition
Alternatives to Blood Transfusion in Transfusion Medicine, Second Edition, Second Edition pdf free by

Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical se...

Transfusion Medicine, Third Edition
Transfusion Medicine, Third Edition free pdf by Jeffrey McCullough(auth.)

Transfusion Medicine offers a concise, clinically focused and practical approach to this important area of medicine. This well-known handbook presents the experience of a world leader in the field of blood banking and transfusion therapy. Transfusion Medi...

Reproductive Immunology
Reproductive Immunology pdf free by D. R. P. Tulsiani (auth.), Satish K. Gupta (eds.)

Reproductive Immunology is a compilation of research articles presented during the VII International Congress of Reproductive Immunology which was held in New Delhi, India on 27-30 October 1998. The articles pertain to the following six major themes: Mole...

Cellular Engineering and Cellular Therapies: Proceedings of the Twenty-Seventh International Symposium on Blood Transfusion, Groningen, Organized by the Sanquin Division Blood Bank North-East, Groningen
Cellular Engineering and Cellular Therapies: Proceedings of the Twenty-Seventh International Symposium on Blood Transfusion, Groningen, Organized by the Sanquin Division Blood Bank North-East, Groningen pdf free by L. F. M. H. de Leij, M. J. A. van Luyn, M. C. Harmsen (auth.), C. Th. Smit Sibinga, L. F. M. H. De Leij (eds.)

Welcome to the City of Groningen, the center of the North of the Netherlands. Groningen is proud of the long lasting tradition of scientific symposia organised by the Sanquin Blood Bank. These Sanquin International Symposia on Blood Transfusion have becom...

Keratinocyte Growth Factor
Keratinocyte Growth Factor download pdf by Farrell C.L., Scully S., Danilenko D.M.

Keratinocyte growth factor (KGF) is a member of the fibroblast growth factor family whose specificity for epithelial tissues is a consequence of the restricted expression of its receptor, KGF receptor (also known as FGFR2IIIb), on epithelial cells. KGF is...

Modern Philosophy: From Descartes to Leibnitz
Modern Philosophy: From Descartes to Leibnitz epub download by Frederick Copleston

Conceived originally as a serious presentation of the development of philosophy for Catholic seminary students, Frederick Copleston's nine-volume A History Of Philosophy has journeyed far beyond the modest purpose of  its author to universal acclaimas the...

Modern Physical Chemistry: A Molecular Approach
Modern Physical Chemistry: A Molecular Approach free download by George H. Duffey (auth.)

In this new textbook on physical chemistry, fundamentals are introduced simply yet in more depth than is common. Topics are arranged in a progressive pattern, with simpler theory early and more complicated theory later. General principles are induced from...

Modern Vaccinology
Modern Vaccinology free download by Edouard Kurstak (auth.), Edouard Kurstak (eds.)

The recent developments in modern vaccinology are mainly based on: (i) cloning of microbial genes into recombinant vectors containing genetic information for expression of desired neutralizing immunogens; (ii) alternatives of attenuated vectors with delet...

Modern Stone Cladding: Design and Installation of Exterior Dimension Stone Systems
Modern Stone Cladding: Design and Installation of Exterior Dimension Stone Systems epub download by Michael D. Lewis

Shows you how to select, design, and install stone cladding systems for exterior walls. New engineering applications as well as recognized industry practices are explained extensively to help you make objective and rational decisions. Section I, Introduct...

Modern Electronic Test Equipment
Modern Electronic Test Equipment pdf free by Keith Brindley (Auth.)

Substantially revised to incorporate changes in the world of test equipment, this book brings together the varieties of instruments including new developments such as time domain reflectometers, automatic test equipment and instrument buses, particularly ...

Modern Chinese Defence Strategy: Present Developments, Future Directions

Modern and Post-Modern Mime
Modern and Post-Modern Mime download pdf by Thomas Leabhart (auth.)

Modern Communication Systems
Modern Communication Systems download pdf by R. F. W. Coates (auth.)

Modern American Reading Practices: Between Aesthetics and History

Models of Capitalism in the European Union: Post-crisis Perspectives
Models of Capitalism in the European Union: Post-crisis Perspectives download pdf by Beáta Farkas (auth.)

This book uses comparative economic analysis to provide a common conceptual framework for all current European Union member states. Based on empirical investigation, the author identifies the Nordic, North-western, Mediterranean, and Central and Eastern m...